Durand Lab


    Selected Publications
 

    Durand Lab Software
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Family classification without domain chaining
  J. M. Joseph and D. Durand, 2009. Bioinformatics 25(12):i45-i53; doi:10.1093/bioinformatics/btp207

Gene cluster statistics with gene families
  N. Raghupathy and D. Durand, 2009. Molecular Biology and Evolution 26: 957-968.

Sequence Similarity Network Reveals Common Ancestry of Multidomain Proteins
  N. Song, J. M. Joseph, G. D. Davis, and D. Durand, 2008. PLoS Comput Biol 4(5): e1000063.
Links to commentaries: Bioinform, Nature Reviews Genetics.

Reconciliation with Non-Binary Species Trees
  B. Vernot, M. Stolzer, A. Goldman, D. Durand. 2008. Journal of Computational Biology, 15(8):981-1006.

Two plus two does not equal three: Statistical Tests for Multiple Genome Comparison
  N. Raghupathy, R. Hoberman and D. Durand, 2008. Journal of Bioinformatics and Computational Biology, 6(1): 1-22.

Domain Architecture Comparison for Multidomain Homology Identification
  N. Song, R.D. Sedgewick and D. Durand, 2007. Journal of Computational Biology, 14(4): 496-516.

Diagnosing duplications: can it be done?
 D. Durand and R. Hoberman, 2006.   Trends in Genetics, Mar;22(3):156-64.

A Hybrid Micro-Macroevolutionary Approach to Gene Tree Reconstruction.
  D. Durand, B. V. Halldorsson, B. Vernot, 2006. Journal of Computational Biology, 13 (2): 320-335.
        A preliminary version appeared in Recomb 2005, LNBI 3500, Springer Verlag, 250-264.
    Notung 2.0

 

Graph Theoretical Insights into Evolution of Multidomain Proteins
  T. Przytycka, G. B. Davis, N. Song and D. Durand, 2006. Journal of Computational Biology, 13 (2): 351-363.
        A preliminary version appeared in Recomb 2005, LNBI 3500, Springer Verlag, 311-325.

The Incompatible Desiderata of Gene Cluster Properties
  R. Hoberman and D. Durand, 2005. RECOMB Workshop on Comparative Genomics, McLysaght and Huson, Eds., Lecture Notes in Bioinformatics vol. 3678, Springer-Verlag, pp. 73-87.

Individual Gene Cluster Statistics in Noisy Maps.
  N. Raghupathy and D. Durand, 2005. RECOMB Workshop on Comparative Genomics, McLysaght and Huson, Eds., Lecture Notes in Bioinformatics vol. 3678, Springer-Verlag, pp. 106-120.

The Statistical Analysis of Spatially Clustered Genes under the Maximum Gap Criterion
  R. Hoberman, D. Sankoff and D. Durand, 2005. Journal of Computational Biology, 12(8): 1081-1100.
    Link to Mathematica code.

 

The Statistical Significance of Max-Gap Clusters.
  R. Hoberman, D. Sankoff and D. Durand, 2004. RECOMB Workshop on Comparative Genomics, J. Lagergren, ed., Lecture Notes in Bioinformatics, Vol. 3388, Springer Verlag, pp. 55 - 71

Tests for Gene Clustering.
  D. Durand and D. Sankoff, 2003.   Journal of Computational Biology, 10 (3/4): 453-482.

Vertebrate evolution: doubling and shuffling with a full deck.
 D. Durand, 2003.   Trends in Genetics, Jan;19(1):2-5.

On the Design of Optimization Criteria for Multiple Sequence Alignment.
  D. Durand and M. Farach-Colton, 2002. In "Biological Evolution and Statistical Physics," M. Lassig and A. Valleriani, eds. Springer Verlag, 22-36.

Notung: A Program for Dating Gene Duplications and Optimizing Gene Family Trees.
  K. Chen, D. Durand and M.  Farach-Colton, 2000. Journal of Computational Biology, 7 (3/4), 429-447.

Impact of Migration and Fitness on the Stability of a Lethal t-haplotype Polymorphism in House Mice: A Computer Study.
  D. Durand, K. Ardlie, L.Buttel, S.A. Levin and L. M. Silver, 1997. Genetics 145, 1093-1108