METABOLISM (1066 ORFs) 
amino acid metabolism (204 ORFs) 
amino acid biosynthesis (118 ORFs) 
biosynthesis of the aspartate family (1 ORF) 
biosynthesis of lysine (1 ORF) 
biosynthesis of the cysteine-aromatic group (2 ORFs) 
biosynthesis of serine (1 ORF) 
"biosynthesis of the pyruvate family (alanine, isoleucine, leucine, valine) and D-alanine (1 ORF)" 
regulation of amino acid metabolism (33 ORFs) 
amino acid transport (23 ORFs) 
amino acid degradation (catabolism) (35 ORFs) 
degradation of amino acids of the glutamate group (1 ORF) 
degradation of glutamate (1 ORF) 
degradation of amino acids of the cysteine-aromatic group (1 ORF) 
degradation of glycine (1 ORF) 
other amino acid metabolism activities (5 ORFs) 
nitrogen and sulfur metabolism (67 ORFs) 
nitrogen and sulfur utilization (38 ORFs) 
regulation of nitrogen and sulphur utilization (29 ORFs) 
nucleotide metabolism (148 ORFs) 
purine ribonucleotide metabolism (45 ORFs) 
pyrimidine ribonucleotide metabolism (29 ORFs) 
deoxyribonucleotide metabolism (11 ORFs) 
metabolism of cyclic and unusual nucleotides (8 ORFs) 
regulation of nucleotide metabolism (13 ORFs) 
polynucleotide degradation (27 ORFs) 
RNA degradation (4 ORFs) 
nucleotide transport (14 ORFs) 
other nucleotide-metabolism activities (7 ORFs) 
phosphate metabolism (33 ORFs) 
phosphate utilization (14 ORFs) 
regulation of phosphate utilization (8 ORFs) 
phosphate transport (10 ORFs) 
other phosphate metabolism activities (1 ORF) 
C-compound and carbohydrate metabolism (415 ORFs) 
C-compound and carbohydrate utilization (261 ORFs) 
"C-compound, carbohydrate anabolism (1 ORF)" 
polysaccharide biosynthesis (1 ORF) 
regulation of C-compound and carbohydrate utilization (120 ORFs) 
"C-compound, carbohydrate transport (42 ORFs)" 
"other C-compound, carbohydrate metabolism activities (2 ORFs)" 
"lipid, fatty-acid and isoprenoid metabolism (213 ORFs)" 
"lipid, fatty-acid and isoprenoid biosynthesis (119 ORFs)" 
phospholipid biosynthesis (2 ORFs) 
glycolipid biosynthesis (1 ORF) 
isoprenoid biosynthesis (1 ORF) 
"tetracyclic and pentacyclic triterpenes (cholesterin, steroids and hopanoids) biosynthesis (1 ORF)" 
"breakdown of lipids, fatty acids and isoprenoids (25 ORFs)" 
"lipid, fatty-acid and isoprenoid utilization (26 ORFs)" 
"regulation of lipid, fatty-acid and isoprenoid metabolism (20 ORFs)" 
lipid and fatty-acid transport (21 ORFs) 
"other lipid, fatty-acid and isoprenoid metabolism activities (13 ORFs)" 
"metabolism of vitamins, cofactors, and prosthetic groups (86 ORFs)" 
"biosynthesis of vitamins, cofactors, and prosthetic groups (63 ORFs)" 
"utilization of vitamins, cofactors, and prosthetic groups (7 ORFs)" 
"regulation of vitamins, cofactors, and prosthetic groups metabolism (3 ORFs)" 
"transport of vitamins, cofactors, and prosthetic groups (3 ORFs)" 
"other vitamin, cofactor, and prosthetic group metabolism activities (8 ORFs)" 
secondary metabolism (5 ORFs) 
metabolism of primary metabolic sugars derivatives (1 ORF) 
biosynthesis of glycosides (1 ORF) 
biosynthesis of secondary products derived from primary amino acids (4 ORFs) 
biosynthesis of amines (4 ORFs) 
ENERGY (252 ORFs) 
glycolysis and gluconeogenesis (35 ORFs) 
pentose-phosphate pathway (9 ORFs) 
"tricarboxylic-acid pathway (citrate cycle, Krebs cycle, TCA cycle) (25 ORFs)" 
electron transport and membrane-associated energy conservation (2 ORFs) 
accessory proteins of electron transport and membrane-associated energy conservation (1 ORF) 
other electron transport and membrane-associated energy conservation proteins (1 ORF) 
respiration (88 ORFs) 
fermentation (33 ORFs) 
"metabolism of energy reserves (glycogen, trehalose) (37 ORFs)" 
glyoxylate cycle (6 ORFs) 
oxidation of fatty acids (7 ORFs) 
other energy generation activities (16 ORFs) 
CELL CYCLE AND DNA PROCESSING (628 ORFs) 
DNA processing (251 ORFs) 
DNA synthesis and replication (94 ORFs) 
DNA recombination and DNA repair (153 ORFs) 
DNA repair (88 ORFs) 
other DNA repair (1 ORF) 
DNA restriction or modification (32 ORFs) 
chromatin modification (32 ORFs) 
cell cycle (451 ORFs) 
mitotic cell cycle and cell cycle control (352 ORFs) 
"cell cycle checkpoints (checkpoints of morphogenesis, DNA-damage,-replication, mitotic phase and spindle) (27 ORFs)" 
meiosis (104 ORFs) 
cytokinesis (cell division) (35 ORFs) 
nuclear and chromosomal cycle (3 ORFs) 
chromosome condensation (1 ORF) 
chromosome segregation (2 ORFs) 
other cell division and DNA synthesis activities (6 ORFs) 
TRANSCRIPTION (771 ORFs) 
rRNA transcription (109 ORFs) 
rRNA synthesis (39 ORFs) 
rRNA processing (63 ORFs) 
other rRNA-transcription activities (6 ORFs) 
tRNA transcription (83 ORFs) 
tRNA synthesis (24 ORFs) 
tRNA processing (36 ORFs) 
tRNA modification (18 ORFs) 
other tRNA-transcription activities (4 ORFs) 
mRNA transcription (556 ORFs) 
mRNA synthesis (406 ORFs) 
general transcription activities (68 ORFs) 
transcriptional control (334 ORFs) 
"mRNA processing (splicing, 5'-, 3'-end processing) (142 ORFs)" 
splicing (101 ORFs) 
3'-end processing (2 ORFs) 
other mRNA-transcription activities (9 ORFs) 
RNA transport (27 ORFs) 
other transcription activities (57 ORFs) 
PROTEIN SYNTHESIS (359 ORFs) 
ribosome biogenesis (215 ORFs) 
translation (64 ORFs) 
initiation (2 ORFs) 
elongation (2 ORFs) 
translational control (31 ORFs) 
aminoacyl-tRNA-synthetases (37 ORFs) 
other protein-synthesis activities (16 ORFs) 
"PROTEIN FATE (folding, modification, destination) (595 ORFs)" 
protein folding and stabilization (59 ORFs) 
"protein targeting, sorting and translocation (146 ORFs)" 
protein modification (187 ORFs) 
"modification with fatty acids (e.g. myristylation, palmitylation, farnesylation) (1 ORF)" 
modification with sugar residues (e.g. glycosylation) (2 ORFs) 
"modification by phosphorylation, dephosphorylation (6 ORFs)" 
"modification by acetylation, deacetylation (4 ORFs)" 
protein processing (proteolytic) (1 ORF) 
other protein modifications (6 ORFs) 
assembly of protein complexes (95 ORFs) 
proteolytic degradation (160 ORFs) 
cytoplasmic and nuclear degradation (99 ORFs) 
proteasomal degradation (1 ORF) 
lysosomal and vacuolar degradation (19 ORFs) 
vacuolar degradation (1 ORF) 
other proteolytic degradation (15 ORFs) 
other protein fate related activities (8 ORFs) 
CELLULAR TRANSPORT AND TRANSPORT MECHANISMS (495 ORFs) 
nuclear transport (59 ORFs) 
mitochondrial transport (80 ORFs) 
"vesicular transport (Golgi network, etc.) (129 ORFs)" 
peroxisomal transport (16 ORFs) 
vacuolar transport (56 ORFs) 
"extracellular transport, exocytosis and secretion (38 ORFs)" 
cellular import (100 ORFs) 
cytoskeleton-dependent transport (27 ORFs) 
other intracellular transport activities (32 ORFs) 
CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION MECHANISM (59 ORFs) 
intracellular signalling (55 ORFs) 
unspecified signal transduction (4 ORFs) 
enzyme mediated signal transduction (12 ORFs) 
G-protein mediated signal transduction (12 ORFs) 
second messenger mediated signal transduction (2 ORFs) 
polyphosphoinositol mediated signal transduction (1 ORF) 
other intracellular signal transduction activities (37 ORFs) 
transmembrane signal transduction (4 ORFs) 
"CELL RESCUE, DEFENSE AND VIRULENCE (278 ORFs)" 
stress response (175 ORFs) 
detoxification (102 ORFs) 
detoxification involving cytochrome P450 (4 ORFs) 
other detoxification (2 ORFs) 
degradation of foreign (exogenous) compounds (1 ORF) 
degradation of foreign (exogenous) polynucleotides (1 ORF) 
other cell rescue activities (9 ORFs) 
REGULATION OF / INTERACTION WITH CELLULAR ENVIRONMENT (199 ORFs) 
ionic homeostasis (127 ORFs) 
homeostasis of cations (117 ORFs) 
"homeostasis of metal ions (Na, K, Ca etc.) (62 ORFs)" 
homeostasis of protons (36 ORFs) 
homeostasis of other cations (23 ORFs) 
homeostasis of anions (13 ORFs) 
homeostasis of sulfates (3 ORFs) 
homeostasis of phosphate (7 ORFs) 
homeostasis of chloride (2 ORFs) 
homeostasis of other anions (1 ORF) 
cellular sensing and response (73 ORFs) 
chemoperception and response (73 ORFs) 
perception of nutrients and nutritional adaptation (25 ORFs) 
pheromone response (37 ORFs) 
osmosensing (17 ORFs) 
CELL FATE (427 ORFs) 
cell growth / morphogenesis (96 ORFs) 
directional cell growth (morphogenesis) (28 ORFs) 
other morphogenetic activities (12 ORFs) 
cell differentiation (382 ORFs) 
fungal cell differentiation (382 ORFs) 
"budding, cell polarity and filament formation (170 ORFs)" 
"pheromone response, mating-type determination, sex-specific proteins (160 ORFs)" 
sporulation and germination (114 ORFs) 
cell death (10 ORFs) 
apoptosis (type I programmed cell death) (1 ORF) 
anti-apoptosis (1 ORF) 
cell aging (4 ORFs) 
"TRANSPOSABLE ELEMENTS, VIRAL AND PLASMID PROTEINS (116 ORFs)" 
"other transposable elements, viral and plasmid proteins (3 ORFs)" 
CONTROL OF CELLULAR ORGANIZATION (209 ORFs) 
cell wall (107 ORFs) 
plasma membrane (1 ORF) 
cytoplasm (1 ORF) 
cytoskeleton (23 ORFs) 
endoplasmic reticulum (3 ORFs) 
Golgi (3 ORFs) 
intracellular transport vesicles (1 ORF) 
nucleus (31 ORFs) 
organization of chromosome structure (18 ORFs) 
mitochondrion (17 ORFs) 
peroxisome (4 ORFs) 
endosome (1 ORF) 
vacuole or lysosome (18 ORFs) 
other control of cellular organization (7 ORFs) 
SUBCELLULAR LOCALISATION (2258 ORFs) 
cell wall (38 ORFs) 
plasma membrane (145 ORFs) 
cytoplasm (554 ORFs) 
cytoskeleton (108 ORFs) 
centrosome (31 ORFs) 
endoplasmic reticulum (157 ORFs) 
Golgi (82 ORFs) 
intracellular transport vesicles (42 ORFs) 
nucleus (774 ORFs) 
chromosome (44 ORFs) 
mitochondrion (366 ORFs) 
peroxisome (39 ORFs) 
endosome (12 ORFs) 
vacuole or lysosome (59 ORFs) 
extracellular / secretion proteins (20 ORFs) 
prokaryotic cell membrane (inner membrane of gram - bacteria) (1 ORF) 
other subcellular localisation (8 ORFs) 
PROTEIN ACTIVITY REGULATION (13 ORFs) 
target of regulation (13 ORFs) 
regulator of G-protein signalling (13 ORFs) 
PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic) (4 ORFs) 
protein binding (3 ORFs) 
lipid binding (1 ORF) 
TRANSPORT FACILITATION (313 ORFs) 
channel / pore class transporters (6 ORFs) 
ion channels (6 ORFs) 
ion transporters (79 ORFs) 
cation transporters (62 ORFs) 
"heavy metal ion transporters (Cu, Fe, etc.) (23 ORFs)" 
"other cation transporters (Na, K, Ca , NH4, etc.) (39 ORFs)" 
"anion transporters (Cl, SO4, PO4, etc.) (21 ORFs)" 
C-compound and carbohydrate transporters (46 ORFs) 
other C-compound transporters (2 ORFs) 
amino-acid transporters (25 ORFs) 
peptide transporters (1 ORF) 
lipid transporters (7 ORFs) 
nucleotide transporters (15 ORFs) 
allantoin and allantoate transporters (9 ORFs) 
drug transporters (35 ORFs) 
transport mechanism (74 ORFs) 
transport ATPases (45 ORFs) 
ABC transporters (28 ORFs) 
other transport mechanisms (1 ORF)